Friday, October 28, 2011

Journal article: Our insights into the structure and activation mechanism of ErbB/EGFR protein kinases

Here's an article my lab published in PLoS One:
Co-Conserved Features Associated with cis Regulation of ErbB Tyrosine Kinases

I'll give a quick summary of it here. (Don't worry, this isn't a new direction for this blog.)

This is a study of the structural mechanisms of a certain protein family, called ErbB or EGFR (epidermal growth factor receptor), which is frequently involved in cancer. This family belongs to a protein superfamily called protein kinases.